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Clinical and Immunological Features and Arthritic Status of Patients' Relatives with First and Second Degree of Kinship Suffering from Rheumatoid Arthritis

Abstract

Pain in the joints was noted in 13 (26,5%) subjects; morning stiffness up to more than 30 minutes for 1 subject (2,0%). Tenderness and swelling in the joints were detected in 15 patients (30,6%). 20 subjects (40,8%) were positive for ACCP or MCV: increased level of ACCP was determined in 5 people (10,2%), MCV - in 19 subjects (38,8%); ACCP and MCV in 4 relatives (8,2%); CRP - in 1 patient (4.,1%), RF was negative for all subjects. In 55% of cases (n=11) a positivite immunological marker was accompanied by the presence of an articular syndrome and in 45% of cases (n=9) it was asymptomatic. MRI revealed the presence of changes in 20,4% of cases (n=10). Erosion was found in 8 of 15 patients with joint syndrome (53,3%); presence of synovitis - in 9 patients (60,0%), signs of bone edema - in 26,6% of cases (n = 4).

About the Authors

N. A. Martusevich
Belarusian State Medical University
Belarus


E. A. Dmitrieva
Healthcare Institution «Clinical hospital No.6»
Belarus


N. P. Mitkovskaya
Belarusian State Medical University
Belarus


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For citations:


Martusevich N.A., Dmitrieva E.A., Mitkovskaya N.P. Clinical and Immunological Features and Arthritic Status of Patients' Relatives with First and Second Degree of Kinship Suffering from Rheumatoid Arthritis. Emergency Cardiology and Cardiovascular Risks journal. 2017;1(1):105-111. (In Russ.)

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