Cardiovascular Risk Stratification in Patients with Rheumatoid Arthritis
Abstract
Patients with rheumatoid arthritis are characterized by left ventricular remodeling with the development of its hypertrophy, diastolic dysfunction and a large-scale carotid and coronary atherosclerosis. Systemic inflammation in patients with rheumatoid arthritis promotes increases in blood levels of soluble intercellular adhesion molecule-1 and matrix metalloproteinase-9. The most informative features that determine the degree of coronary and carotid atherosclerosis in patients with rheumatoid arthritis are indicators of inflammatory activity (high-sen¬sitivity C-reactive protein levels, the index DAS 28), the content of brain natriuretic peptide, age and presence of hypertension.
About the Authors
T. A. KurakBelarus
L. L. Avdej
Belarus
T. V. Iljina
Belarus
E. G. Oganova
Belarus
E. I. Shkrebneva
Belarus
Zh. N. Kot
Belarus
L. V. Kartun
Belarus
N. P. Mitkovskaya
Belarus
References
1. Naranjo A., SokkaT., Descalzo M.A., Calvo-Alen J.,Horslev-Petersen K., Luukkainen R.K., Combe B., Burmester G. R., Devlin J., Ferraccioli G., Morelli A., Hoekstra M., Majdan M., Sadkiewicz S., Belmonte M., Holmqvist A. C., Choy E., Tunc R., Dimic A., Bergman M., Toloza S., Pincus T. Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study. Arthritis Res Ther, 2008, vol. 10, no. 2, pp. 30.
2. Assous N., Touze E., Meune C., Kahan A., Allanore Y. Cardiovascular disease in rheumatoid arthritis: single-center hospital based cohort study in France. Joint Bone Spine, 2007, vol. 74, no. 1, pp. 66-72.
3. Full L. E., Ruisanchez C., Monaco C. The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus.
4. Arthritis Res Ther, 2009, vol. 11, no. 2, pp. 217.
5. Maradit-Kremers H., Crowson C. S., Nicola P. J., Ballman K. V., Roger V. L., Jacobsen S. J., Gabriel S. E. Increased unrecognized coronary heart disease and sudden deaths in rheumatoid arthritis: a population-based cohort study. Arthritis Rheum, 2005, vol. 52, no. 2, pp. 402-411.
6. Nicola P. J., Maradit-Kremers H., Roger V. L., Jacobsen S. J., Crowson C. S., Ballman K. V., Gabriel S. E. The risk of congestive heart failure in rheumatoid arthritis: a population-based study over 46 years. Arthritis Rheum, 2005, vol. 52, no. 2, pp. 412-420.
7. Warrington K. J., Kent P. D., Frye R. L., Lymp J. F., Kopecky S. L., Goronzy J. J., Weyand C. M. Rheumatoid arthritis is an independent risk factor for multi-vessel coronary artery disease: a case control study. Arthritis Res Ther, 2005, vol. 7, no. 5, pp. 984-991.
8. Aubry M. C., Maradit-Kremers H., Reinalda M. S., Crowson C. S., Edwards W. D., Gabriel S. E. Differences in atherosclerotic coronary heart disease between subjects with and without rheumatoid arthritis. J Rheumatol, 2007, vol. 34, no. 5, pp. 937-942.
9. Sodergren A., Stegmayr B., Lundberg V., Ohman M. L., Wallberg-Jonsson S. Increased incidence of and impaired prognosis after acute myocardial infarction among patients with seropositive rheumatoid arthritis. Ann RheumDis, 2007, vol. 66, no. 2, pp. 263-266.
10. Lorenz M. W., von Kegler S., Steinmetz H., Markus H. S., Sitzer M. Carotid intima-media thickening indicates a higher vascular risk across a wide age range: prospective data from the Carotid Atherosclerosis Progression Study (CAPS). Stroke, 2006, vol. 37, pp. 87-92.
11. Kulikov V. P. Ultrasound diagnosis of vascular diseases [Ultrasound diagnosis of vascular diseases]. Moscow, STROM, 2007, 512 p. (in Russian).
12. George A., Movahed A. Coronary Artery Calcium Scores: Current Thinking and Clinical Applications. Open Cardiovasc Med J, 2008, vol. 2, pp. 87-92.
Review
For citations:
Kurak T.A., Avdej L.L., Iljina T.V., Oganova E.G., Shkrebneva E.I., Kot Zh.N., Kartun L.V., Mitkovskaya N.P. Cardiovascular Risk Stratification in Patients with Rheumatoid Arthritis. Emergency Cardiology and Cardiovascular Risks journal. 2017;1(1):99-104. (In Russ.)









