The state of vascular-platelet hemostasis in children with arterial hypertension
Abstract
The purpose of the study was to study the state of primary hemostasis in children with arterial hypertension (AH) and assess the effect on obesity, weighed heredity of atherosclerosis. The study of primary hemostasis was performed by studying the number and function of platelets among 146 children with hypertension. Of these, 49 children had concomitant obesity, 53 children had hereditary atherosclerosis and 44 children had AH without concomitant pathology. Children with AH have an increase of the aggregation process at more pronounced at low concentrations of the ADP solution (0.5 mmol / L) and enhancing the adhesive properties of the platelets themselves. Obesity promotes maximum growth of adhesive-aggregation potential of platelets in children with AH. The presence of weighed heredity in atherosclerosis in patients with AH promoted a more pronounced increase in aggregation and adhesive properties of platelets, caused by dyslipidemia, hereditary predisposition.
About the Authors
V. V. Strogiy
Belarusian State Medical University
Belarus
Belarus
O. N. Volkova
Belarusian State Medical University
Belarus
Belarus
V. D. Yushko
Belarusian State Medical University
Belarus
Belarus
E. V. Kilchevskaya
Учреждение здравоохранения «2-я детская клиническая больница»
Belarus
Belarus
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Review
For citations:
Strogiy V.V., Volkova O.N., Yushko V.D., Kilchevskaya E.V. The state of vascular-platelet hemostasis in children with arterial hypertension. Emergency Cardiology and Cardiovascular Risks journal. 2018;2(2):387-391. (In Russ.)
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