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Segmental hypoplasia of the vertebral artery: a case report

https://doi.org/10.51922/2616-633X.2025.9.2.2652

Abstract

The article describes a case of congenital hypoplasia of the left vertebral artery in a 57-year-old patient in combination with a cerebral infarction caused by vertebrobasilar insufficiency. Concomitant diseases: arterial hypertension, dyslipidemia, impaired fat metabolism (BMI – 33 kg/m2), high-risk coronary heart disease according to the SCORE scale. On the eve of hospitalization, he noted a short-term loss of consciousness when bending forward and impaired coordination of movements. Objective status: muscle strength was preserved in all muscle groups; muscle tone was not changed; sensory disorders were absent; he staggered in the Romberg pose; performed the finger test satisfactorily on both sides; his gait was uncertain. CT scans of the vessels of the neck and brain with angiography revealed a narrowing of the left vertebral artery. Its diameter is almost 1/3 smaller than that of similar sections of the right vertebral artery and varies from 1 mm at the C1 level to 2.5 mm in the V4 segment. A defect in the contrast of the left vertebral artery was found due to prolonged soft atherosclerotic plaque without signs of calcification. The left internal carotid artery has an S-shaped bend in the extracranial region at the C1–C2 level. At the mouth of the right internal carotid artery (at the level of the bifurcation of the right common carotid artery), a parietal calcified atherosclerotic plaque with a narrowing of the lumen to 15 % is detected. An MRI scan of the brain revealed a pattern of infarction of the left hemisphere of the cerebellum.

Conclusion: congenital asymptomatic hypoplasia of the vertebral artery is a risk factor for the development of cerebral circulatory disorders. The progression of systemic atherosclerotic vascular lesions contributes to the development of vertebrobasilar stroke.

About the Authors

Т. I. Kalenchic
Belarusian State Medical University
Belarus

Minsk



S. L. Kabak
Belarusian State Medical University
Belarus

Minsk



V. V. Zatochnaya
Belarusian State Medical University
Belarus

Minsk



M. V. Pravasud
City clinical hospital of emergency medical care of Minsk
Belarus

Minsk



N. S. Didenko
A.N. Bakulev, Center for cardiovascular surgery of the Russian Ministry of Health
Russian Federation

Moscow



References

1. Bakalarz M., Rożniecki J.J., Stasiołek M. Clinical characteristics of patients with vertebral artery hypoplasia. Int J Environ Res Public Health. 2022, vol.19, no. 15, pp. 9317. doi: 10.3390/ijerph19159317.

2. Tudose R.C., Rusu M.C., Hostiuc S. The vertebral artery: a systematic review and a meta-analysis of the current literature. Diagnostics (Basel). 2023, vol. 13, no. 12, pp. 2036. doi: 10.3390/diagnostics13122036.

3. Ergun O., Gunes Tatar I., Birgi E., Hekimoglu B. Evaluation of vertebral artery dominance, hypoplasia and variations in the origin: angiographic study in 254 patients. Folia Morphol (Warsz). 2016, vol. 75, no. 1, pp. 33-37. doi: 10.5603/FM.a2015.0061).

4. Furtado G.D., Costa M.A.J., Costa S.E.J., Sobral F.E.S., Maia C.M.A.F.G., Oliveira J.A. Anatomical variations of the vertebral artery and their implications. Environmental Smoke, 2024, vol. 7, manuscript ID: es20240005 (1-6). doi:10.32435/envsmoke-2024-0005.

5. Siedlecki Z., Szostak M., Nowak K., Śniegocki M. Atypical course of vertebral artery outside the cervical spine: case report and review of the literature. World Neurosurg. 2021, vol. 145, pp. 405-408. doi: 10.1016/j.wneu.2020.10.028.

6. Mysior M., Majos A., Stefańczyk L. Vertebral artery hypoplasia – diagnostic criteria based on the haemodynamics of the vertebro-basilar circulation. Menopause Review/ Przegląd Menopauzalny, 2007, vol. 6, no. 6, pp. 371-375.

7. Chuang Y.M., Chan L., Wu H.M., Lee S.P., Chu Y.T. The clinical relevance of vertebral artery hypoplasia. Acta Neurol Taiwan. 2012, vol. 21, no. 1, pp. 1–7.

8. Valenzuela-Fuenzalida J.J., Rojas-Navia C.P., Quirós-Clavero A.P., Sanchis-Gimeno J., Rodriguez-Luengo M., Nova-Baeza P., Orellana-Donoso M., Becerra Farfán Á., Bruna-Mejias A., Sepúlveda-Loyola W., Iwanaga J. Anatomy of vertebral artery hypoplasia and its relationship with clinical implications: a systematic review and meta-analysis of prevalence. Surg Radiol Anat. 2024, vol. 46, no. 7, pp. 963-975. doi: 10.1007/s00276-024-03377-y.

9. Thierfelder K.M., Baumann A.B., Sommer W.H., Armbruster M., Opherk C., Janssen H., Reiser M.F., Straube A., von Baumgarten L. Vertebral artery hypoplasia: frequency and effect on cerebellar blood flow characteristics. Stroke. 2014, vol. 45, no. 5, pp.1363-1368. doi: 10.1161/STROKEAHA.113.004188.

10. Dinç Y., Özpar R., Emir B., Hakyemez B., Bakar M. Vertebral artery hypoplasia as an independent risk factor of posterior circulation atherosclerosis and ischemic stroke. Medicine (Baltimore). 2021, vol. 100, no. 38, p. e27280. doi: 10.1097/MD.0000000000027280.

11. Layegh P., Jarahi L., Hassannejad E., Arab M. The association between vertebral artery hypoplasia and fetal-type variants of the posterior cerebral artery with imaging findings among patients with posterior circulation stroke: a single-center cross-sectional study. Health Sci Rep. 2024, vol. 7, no. 2, p. e1918. doi: 10.1002/hsr2.1918.

12. Katsanos A.H., Kosmidou M., Kyritsis A.P., Giannopoulos S. Is vertebral artery hypoplasia a predisposing factor for posterior circulation cerebral ischemic events? A comprehensive review. Eur Neurol. 2013, vol. 70, no. 1-2, pp. 78-83. doi: 10.1159/000351786.

13. Freund W., Kassubek J., Aschoff A.J., Huber R. MRI-based separation of congenital and acquired vertebrobasilar artery anomalies in ischemic stroke of the posterior circulation. Stroke. 2008, vol. 39, no. 8, pp. 2382–2384. doi: 10.1161/STROKEAHA.107.512772.

14. Błaszczyk M., Ochwat K., Necka S,, Kwiecińska M., Ostrowski P., Bonczar M., Żytkowski A., Walocha J., Mituś J., Koziej M. The arterial anatomy of the cerebellum-a comprehensive review. Brain Sci. 2024, vol. 14, no. 8, p. 763. doi: 10.3390/brainsci14080763.

15. Rhoton A.L. Jr. The cerebellar arteries. Neurosurgery. 2000, vol. 47, no. 3 (Suppl), SS. 29-68. doi: 10.1097/00006123-200009001-00010.

16. Benes V., Netuka D. Surgical correction of symptomatic vertebral artery kinking. Br J Neurosurg. 2003, vol. 17, no. 2, pp. 174–178. doi: 10.1080/0268869031000108927.

17. Pizova N.V., Druzhinin D.S., Dmitriev A.N. Hypoplasia of spinal arteries and brain blood circulation disorders. S.S. Korsakov Journal of Neurology and Psychiatry. 2010, vol. 110, no. 7, pp. 56 58. (in Russian).

18. Burle V.S., Panjwani A., Mandalaneni K., Kollu S., Gorantla V.R. Vertebral artery stenosis: a narrative review. Cureus. 2022, vol. 14, no 8, p. e28068. doi: 10.7759/cureus.28068).

19. Bae J.H., Ryu J.C., Ha S.H., Kim B.J., Kang D.W., Kwon S.U., Kim J.S., Chang J.Y. Association of left vertebral artery hypoplasia with posterior circulation stroke and the functional outcome of patients with atrial fibrillation-related cardioembolic Stroke. AJNR Am J Neuroradiol. 2023, vol. 44, no. 1, pp. 65-69. doi: 10.3174/ajnr.A7738.

20. Merwick A., Werring D. Posterior circulation ischaemic stroke. BMJ. 2014; vol. 348: g3175. doi: 10.1136/bmj.g3175.

21. Eremina Y.O., Kulesh A.A., Halo N.V., Astanin P.A. Clinical characteristic and longterm prognosis in vertebrobasilar stroke. Russian neurological journal. 2024, vol. 29, no. 4, pp. 54-61. doi: 10.30629/2658-7947-2024-29-4-54-61. (in Russian).


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For citations:


Kalenchic Т.I., Kabak S.L., Zatochnaya V.V., Pravasud M.V., Didenko N.S. Segmental hypoplasia of the vertebral artery: a case report. Emergency Cardiology and Cardiovascular Risks journal. 2025;9(2):2652-2658. (In Russ.) https://doi.org/10.51922/2616-633X.2025.9.2.2652

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