emcardioНеотложная кардиология и кардиоваскулярные рискиEmergency Cardiology and Cardiovascular Risks journal2616-633XБелорусский государственный медицинский университет10.51922/2616-633X.2024.8.2.2348emcardio-7Research ArticleОбзоры и лекцииReviews and lecturesСистематический обзор и мета-анализ эффективности применения коэнзима Q10 с целью профилактики послеоперационных осложнений при кардиохирургических вмешательствахSystematic review and meta-analysis of the effectiveness of coenzyme Q10 for the prevention of postoperative complications during cardiac surgeryКотовичА. В.KotovichA. V.

 г. Минск 

 Minsk 

alexeykotovich@yandex.byЯкимчукА. П.YakimchukA. P.

 г. Минск 

 Minsk 

МахановскийИ. А.MakhanovskyI. A.

 г. Минск 

 Minsk 

РуммоО. О.RummoO. O.

 г. Минск 

 Minsk 

ДзядзькоА. М.DzyadzkoA. M.

 г. Минск 

 Minsk 

РачокЛ. В.RachokL. V.

 г. Минск 

 Minsk 

ГУ «Минский научно-практический центр хирургии, трансплантологии и гематологии»State Institution “Minsk Scientific and Practical Center for Surgery, Transplantology and Hematology”Belarusian State Medical UniversityBelarus202418062025822348–2354Copyright © Котович А.В., Якимчук А.П., Махановский И.А., Руммо О.О., Дзядзько А.М., Рачок Л.В., 20252025Котович А.В., Якимчук А.П., Махановский И.А., Руммо О.О., Дзядзько А.М., Рачок Л.В.Kotovich A.V., Yakimchuk A.P., Makhanovsky I.A., Rummo O.O., Dzyadzko A.M., Rachok L.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://emcardio.bsmu.by/jour/article/view/7

В данной статье представлены данные проведенного систематического обзора и мета-анализа по эффективности коэнзима Q10 в рамках преабилитации. Оценивались такие исходы как: уровень CK-MB, значение сердечного индекса (CI) через 24 часа после вмешательства, длительность госпитализации уровень hsTroponin и степень вазопрессорной поддержки через 24 часа после кардиохирургического вмешательства. Ввиду множества ограничений, проведенный мета-анализ не показал эффективности коэнзима Q10, что требует исследований надлежащего качества для более подробного изучения данного препарата.

This article presents the data from a systematic review and meta-analysis of the effectiveness of coenzyme Q10 in the framework of preabilitation. The outcomes assessed included: CK-MB level, cardiac index (CI) value 24 hours after intervention, duration of hospitalization, hsTroponin level and degree of vasopressor support 24 hours after cardiac surgery. Due to many limitations, the meta-analysis has not shown the effectiveness of coenzyme Q10, which requires investigations of proper quality for a more detailed study of this drug.

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The authors declare that there are no conflicts of interest present.