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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">emcardio</journal-id><journal-title-group><journal-title xml:lang="ru">Неотложная кардиология и кардиоваскулярные риски</journal-title><trans-title-group xml:lang="en"><trans-title>Emergency Cardiology and Cardiovascular Risks journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2616-633X</issn><publisher><publisher-name>Белорусский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">emcardio-284</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзоры и лекции</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Reviews and lectures</subject></subj-group></article-categories><title-group><article-title>Коморбидные состояния при хронической сердечной недостаточности: как оптимизировать лечение?</article-title><trans-title-group xml:lang="en"><trans-title>Comorbidities in Heart Failure: How to Optimize the Treatment?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чумбуридзе</surname><given-names>В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chumburidze</surname><given-names>V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кикалишвили</surname><given-names>Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Kikalishvili</surname><given-names>T.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Центр неотложной кардиологии им. академика Г. Чапидзе</institution></aff><aff xml:lang="en"><institution>Acad. G. Chapidze Emergency Cardiology Center</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>14</day><month>11</month><year>2025</year></pub-date><volume>2</volume><issue>1</issue><fpage>280</fpage><lpage>290</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чумбуридзе В., Кикалишвили Т., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Чумбуридзе В., Кикалишвили Т.</copyright-holder><copyright-holder xml:lang="en">Chumburidze V., Kikalishvili T.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://emcardio.bsmu.by/jour/article/view/284">https://emcardio.bsmu.by/jour/article/view/284</self-uri><abstract><p>У большинства пациентов, особенно у пожилых, хроническая сердечная недостаточность сопровождается рядом сопутствующих заболеваний, которые играют важную роль в ее развитии и реакции на лечение. Коморбидность определяется как хроническое состояние, которое сосуществует у пациента с другим установленным заболеванием. Различают несердечные патологические состояния и сердечные заболевания, которые непосредственно связаны с наличием хронической сердечной недостаточности, например, аритмии, а также состояния, которые предшествуют и способствуют ее развитию, такие как артериальная гипертензия, сахарный диабет и гиперлипидемия. В статье рассмотрены несердечные патологические состояния и проанализированы общие проблемы коморбидности при хронической сердечной недостаточности. Также приводится информация по конкретным сопутствующим заболеваниям и подходам к терапии хронической сердечной недостаточности. Заключительная часть статьи посвящена проблеме комбинированной лекарственной терапии при лечении пациентов с сопутствующими заболеваниями.</p></abstract><trans-abstract xml:lang="en"><p>In most patients, and particularly in elderly patients, heart failure (HF) is accompanied by a range of comorbidities that play an integral role in its progression and response to treatment. Comorbidity is defined as a chronic condition that coexists in an individual with another condition that is being described. A distinction is made between noncardiac comorbidities and cardiac conditions that are directly related to the presence of HF such as arrhythmias as well as conditions that precede and contribute to its aetiology such as hypertension, diabetes mellitus, and hyperlipidemia. In this article, we will initially focus on noncardiac comorbidities and discuss the general problem of comorbidity in HF. Then we will examine specific comorbidities and how to manage patients with HF in the best way. Finally, we will consider the problem of multidrug therapy when managing patients with comorbidities.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая сердечная недостаточность</kwd><kwd>сопутствующая патология</kwd><kwd>комбинированная лекарственная терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>heart failure</kwd><kwd>comorbidity</kwd><kwd>multidrug therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Chong V.H., Singh J., Parry H., Saunders J., Chowdhury F., Mancini D.M., Lang C.C. Management of Noncardiac Comorbidities in Chronic Heart Failure. Cardiovasc Ther, 2015, vol. 33, no. 5, pp. 300-315. doi: 10.1111/1755-5922.12141.</mixed-citation><mixed-citation xml:lang="en">Chong V.H., Singh J., Parry H., Saunders J., Chowdhury F., Mancini D.M., Lang C.C. Management of Noncardiac Comorbidities in Chronic Heart Failure. 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