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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">emcardio</journal-id><journal-title-group><journal-title xml:lang="ru">Неотложная кардиология и кардиоваскулярные риски</journal-title><trans-title-group xml:lang="en"><trans-title>Emergency Cardiology and Cardiovascular Risks journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2616-633X</issn><publisher><publisher-name>Белорусский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">emcardio-271</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальные научные публикации</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original Scientific Research</subject></subj-group></article-categories><title-group><article-title>Эндоваскулярная окклюзия ушка левого предсердия при неклапанной фибрилляции предсердий</article-title><trans-title-group xml:lang="en"><trans-title>Endovascular left atrial appendage occlusion in nonvalvular atrial fibrillation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Постоялко</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Postojalko</surname><given-names>A. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сивак</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sivak</surname><given-names>S. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кудош</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kudash</surname><given-names>M. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галицкая</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Galitskaya</surname><given-names>S. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Государственное учреждение «Республиканский клинический медицинский центр» Управления делами Президента Республики Беларусь</institution></aff><aff xml:lang="en"><institution>Republican Clinical Medical Centre of the Presidential Administration of the Republic of Belarus</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>13</day><month>11</month><year>2025</year></pub-date><volume>2</volume><issue>2</issue><fpage>373</fpage><lpage>386</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Постоялко А.С., Сивак С.А., Кудош М.И., Галицкая С.С., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Постоялко А.С., Сивак С.А., Кудош М.И., Галицкая С.С.</copyright-holder><copyright-holder xml:lang="en">Postojalko A.S., Sivak S.A., Kudash M.I., Galitskaya S.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://emcardio.bsmu.by/jour/article/view/271">https://emcardio.bsmu.by/jour/article/view/271</self-uri><abstract><p>Цель. Оценить ближайшие и отдаленные результаты пилотного в Беларуси опыта применения окклюдера Watchman у пациентов с неклапанной фибрилляцией предсердий с целью профилактики острого нарушения мозгового кровообращения.</p></abstract><trans-abstract xml:lang="en"><p>The aim of the study was to investigate the immediate and follow up results of the first Belarus experience of transcatheter left atrial appendage occlusion with the Watchman device in patients with nonvalvular atrial fibrillation.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>фибрилляция предсердий</kwd><kwd>эндоваскулярная окклюзия</kwd><kwd>острое нарушение мозгового кровообращения</kwd><kwd>ушко левого предсердия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atrial fibrillation</kwd><kwd>transcatheter occlusion</kwd><kwd>stroke</kwd><kwd>left atrial appendage</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Meier B., Blaauw Y., Khattab A.A., Lewalter T., Sievert H., Tondo C., Glikson M. EHRA/EAPCI expert consensus statement on catheter-based left atrial appendage occlusion. Europace, 2014, vol. 16, № 10, pp. 1397-1416. doi: 10.1093/europace/euu174. Epub 2014 Aug 29.</mixed-citation><mixed-citation xml:lang="en">Meier B., Blaauw Y., Khattab A.A., Lewalter T., Sievert H., Tondo C., Glikson M. EHRA/EAPCI expert consensus statement on catheter-based left atrial appendage occlusion. Europace, 2014, vol. 16, № 10, pp. 1397-1416. doi: 10.1093/europace/euu174. Epub 2014 Aug 29.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ganeeva O.N. Okkljuzija ushka levogo predserdija pri fibrilljacii predserdij [Left atrial appendage occlusion in atrial fibrillation]. Patologija krovoobrashhenija i kardiohirurgija, 2014, vol. 18, № 4, pp. 104-112. (in Russian).</mixed-citation><mixed-citation xml:lang="en">Ganeeva O.N. Okkljuzija ushka levogo predserdija pri fibrilljacii predserdij [Left atrial appendage occlusion in atrial fibrillation]. Patologija krovoobrashhenija i kardiohirurgija, 2014, vol. 18, № 4, pp. 104-112. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Heeringa J, van der Kuip D.A, Hofman A., Kors J.A., van Herpen G., Stricker B.H., Stijnen T., Lip G.Y., Witteman J.C. Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study. Eur Heart J, 2006, vol. 27, № 8, pp. 949-953.</mixed-citation><mixed-citation xml:lang="en">Heeringa J, van der Kuip D.A, Hofman A., Kors J.A., van Herpen G., Stricker B.H., Stijnen T., Lip G.Y., Witteman J.C. Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study. Eur Heart J, 2006, vol. 27, № 8, pp. 949-953.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kishore A., Vail A., Majid A., Dawson J., Lees K.R., Tyrrell P.J., Smith C.J. Detection of atrial fibrillation after ischemic stroke or transient ischemic attack: a systematic review and meta-analysis. Stroke, 2014, vol. 45, № 2, pp. 520-526.</mixed-citation><mixed-citation xml:lang="en">Kishore A., Vail A., Majid A., Dawson J., Lees K.R., Tyrrell P.J., Smith C.J. Detection of atrial fibrillation after ischemic stroke or transient ischemic attack: a systematic review and meta-analysis. Stroke, 2014, vol. 45, № 2, pp. 520-526.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Bedeir K., Holmes D.R., Cox J.L., Ramlawi B. Left atrial appendage exclusion: An alternative to anticoagulation in nonvalvular atrial fibrillation. J Thorac Cardiovasc Surg, 2017, vol. 153, № 5, pp. 1097-105.</mixed-citation><mixed-citation xml:lang="en">Bedeir K., Holmes D.R., Cox J.L., Ramlawi B. Left atrial appendage exclusion: An alternative to anticoagulation in nonvalvular atrial fibrillation. J Thorac Cardiovasc Surg, 2017, vol. 153, № 5, pp. 1097-105.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Chatterjee S., Alexander J.C., Pearson P.J., Feldman T. Left atrial appendage occlusion: lessons learned from surgical and transcatheter experiences. Ann Thorac Surg, 2011, vol. 92, № 6, pp. 2283-2292.</mixed-citation><mixed-citation xml:lang="en">Chatterjee S., Alexander J.C., Pearson P.J., Feldman T. Left atrial appendage occlusion: lessons learned from surgical and transcatheter experiences. Ann Thorac Surg, 2011, vol. 92, № 6, pp. 2283-2292.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Kirchhof P., Benussi S., Kotecha D., Ahlsson A., Atar D., Casadei B., Castella M., Diener H.C., Heidbuchel H., Hendriks J., Hindricks G., Manolis A.S., Oldgren J., Popescu B.A., Schotten U., Van Putte B., Vardas P. ESC Guidelances for the management of atrial fibrillation developed in collaboration with EACTS. Kardiol Pol, 2016, vol. 74, № 12, pp. 1 3 5 9 -1 4 6 9 . doi: 10.5603/ KP.2016.0172.</mixed-citation><mixed-citation xml:lang="en">Kirchhof P., Benussi S., Kotecha D., Ahlsson A., Atar D., Casadei B., Castella M., Diener H.C., Heidbuchel H., Hendriks J., Hindricks G., Manolis A.S., Oldgren J., Popescu B.A., Schotten U., Van Putte B., Vardas P. ESC Guidelances for the management of atrial fibrillation developed in collaboration with EACTS. Kardiol Pol, 2016, vol. 74, № 12, pp. 1 3 5 9 -1 4 6 9 . doi: 10.5603/ KP.2016.0172.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Hart R.G., Pearce L.A., Aguilar M.I. Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med, 2007, vol. 146, № 12, pp. 857-867.</mixed-citation><mixed-citation xml:lang="en">Hart R.G., Pearce L.A., Aguilar M.I. Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med, 2007, vol. 146, № 12, pp. 857-867.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Cooper N.J., Sutton A.J., Lu G., Khunti K. Mixed comparison of stroke prevention treatments in individuals with nonrheumatic atrial fibrillation. Arch Intern Med, 2006, vol. 166, № 12, pp. 1269-1275.</mixed-citation><mixed-citation xml:lang="en">Cooper N.J., Sutton A.J., Lu G., Khunti K. Mixed comparison of stroke prevention treatments in individuals with nonrheumatic atrial fibrillation. Arch Intern Med, 2006, vol. 166, № 12, pp. 1269-1275.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Waldo A.L., Becker R.C., Tapson V.F., Colgan K.J. Hospitalized patients with atrial fibrillation and a high risk of stroke are not being provided with adequate anticoagulation. J Am Coll Cardiol, 2005, vol. 46, № 9, pp. 1729-1736.</mixed-citation><mixed-citation xml:lang="en">Waldo A.L., Becker R.C., Tapson V.F., Colgan K.J. Hospitalized patients with atrial fibrillation and a high risk of stroke are not being provided with adequate anticoagulation. J Am Coll Cardiol, 2005, vol. 46, № 9, pp. 1729-1736.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Brown M.T., Bussel J.K. Medication adherence: WHO cares? Mayo Clin Proc, 2011, vol. 86, № 4, pp. 304-314. doi: 10.4065/mcp.2010.0575. Epub 2011 Mar 9.</mixed-citation><mixed-citation xml:lang="en">Brown M.T., Bussel J.K. Medication adherence: WHO cares? Mayo Clin Proc, 2011, vol. 86, № 4, pp. 304-314. doi: 10.4065/mcp.2010.0575. Epub 2011 Mar 9.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Ruff C.T., Giugliano R.P., Braunvald E., Hoffman E.B., Deenadayalu N., Ezekowitz M.D., Camm A.J., Weitz J.I., Lewis B.S., Parkhomenko A., Yamashita T., Antman E.M. Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a metaanalysis of randomised trials. Lancet, 2014, vol. 383, № 9921, pp. 955­962. doi: 10.1016/S0140-6736(13)62343-0. Epub 2013 Dec 4.</mixed-citation><mixed-citation xml:lang="en">Ruff C.T., Giugliano R.P., Braunvald E., Hoffman E.B., Deenadayalu N., Ezekowitz M.D., Camm A.J., Weitz J.I., Lewis B.S., Parkhomenko A., Yamashita T., Antman E.M. Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a metaanalysis of randomised trials. Lancet, 2014, vol. 383, № 9921, pp. 955­962. doi: 10.1016/S0140-6736(13)62343-0. Epub 2013 Dec 4.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Meier B., Palacios I., Windecker S., Rotter M., Cao Q.L., Keane D., Ruiz C.E., Hijazi Z.M. Transcatheter left atrial appendage closure with Amplatzer devices to obviate anticoagulation in patients with atrial fibrillation. Catheter Cardiovasc Interv, 2011, vol. 60, № 3, pp. 417-422.</mixed-citation><mixed-citation xml:lang="en">Meier B., Palacios I., Windecker S., Rotter M., Cao Q.L., Keane D., Ruiz C.E., Hijazi Z.M. Transcatheter left atrial appendage closure with Amplatzer devices to obviate anticoagulation in patients with atrial fibrillation. Catheter Cardiovasc Interv, 2011, vol. 60, № 3, pp. 417-422.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Shahmatova O.O. Jendovaskuljarnaja okkljuzija ushka levogo predserdija ustrojstvom Watchman kak al’ternativnyj podhod k profilaktike trom - bojembolicheskih oslozhnenij u pacientov s fibrilljaciej predserdij [Transcatheter left atrial appendage occlusion with Watchman device as an alternative method of prevention of thromboembolic events]. Aterotromboz, 2013, № 2, pp. 30-37. (in Russian).</mixed-citation><mixed-citation xml:lang="en">Shahmatova O.O. Jendovaskuljarnaja okkljuzija ushka levogo predserdija ustrojstvom Watchman kak al’ternativnyj podhod k profilaktike trom - bojembolicheskih oslozhnenij u pacientov s fibrilljaciej predserdij [Transcatheter left atrial appendage occlusion with Watchman device as an alternative method of prevention of thromboembolic events]. Aterotromboz, 2013, № 2, pp. 30-37. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Holmes D.R., Doshi S.K., Kar S., Price M.J., Sanchez J.M., Sievert H., Valderrabano M., Reddy V.Y. Left atrial appendage closure as an alternative to warfarin for stroke prevention in atrial fibrillation.: a patient-level metaanalysis. J Am Coll Cardiol, 2015, vol. 65, № 24, pp. 2614-2623. doi: 10.1016/j.jacc.2015.04.025.</mixed-citation><mixed-citation xml:lang="en">Holmes D.R., Doshi S.K., Kar S., Price M.J., Sanchez J.M., Sievert H., Valderrabano M., Reddy V.Y. Left atrial appendage closure as an alternative to warfarin for stroke prevention in atrial fibrillation.: a patient-level metaanalysis. J Am Coll Cardiol, 2015, vol. 65, № 24, pp. 2614-2623. doi: 10.1016/j.jacc.2015.04.025.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Gangireddy S.R., Halperin J.L., Fuster V., Reddy V.Y. Percutaneous left atrial appendage closure for stroke prevention in patients with atrial fibrillation: an assessment of net clinical benefit. Eur Heart J 2012, vol. 33, № 21, pp. 2700-2708. doi: 10.1093/eurheartj/ehs292. Epub 2012 Sep 24.</mixed-citation><mixed-citation xml:lang="en">Gangireddy S.R., Halperin J.L., Fuster V., Reddy V.Y. Percutaneous left atrial appendage closure for stroke prevention in patients with atrial fibrillation: an assessment of net clinical benefit. Eur Heart J 2012, vol. 33, № 21, pp. 2700-2708. doi: 10.1093/eurheartj/ehs292. Epub 2012 Sep 24.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Alli O., Doshi S., Kar S., Reddy V., Sievert H., Mullin C., Swarup V., Whise- nant B., Holmes D.Jr. Quality of life assessment in the randomized PROTECT AF trial of patients at risk for stroke with non-valvular atrial fibrillation. J Am Coll Cardiol, 2013, vol. 61, № 17, pp. 1790-1798. doi: 10.1016/j.jacc.2013.01.061. Epub 2013 Feb 28.</mixed-citation><mixed-citation xml:lang="en">Alli O., Doshi S., Kar S., Reddy V., Sievert H., Mullin C., Swarup V., Whise- nant B., Holmes D.Jr. Quality of life assessment in the randomized PROTECT AF trial of patients at risk for stroke with non-valvular atrial fibrillation. J Am Coll Cardiol, 2013, vol. 61, № 17, pp. 1790-1798. doi: 10.1016/j.jacc.2013.01.061. Epub 2013 Feb 28.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
