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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">emcardio</journal-id><journal-title-group><journal-title xml:lang="ru">Неотложная кардиология и кардиоваскулярные риски</journal-title><trans-title-group xml:lang="en"><trans-title>Emergency Cardiology and Cardiovascular Risks journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2616-633X</issn><publisher><publisher-name>Белорусский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">emcardio-256</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальные научные публикации</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original Scientific Research</subject></subj-group></article-categories><title-group><article-title>Функциональное состояние эндотелия у лиц трудоспособного возраста с синдромом обструктивного апноэ сна</article-title><trans-title-group xml:lang="en"><trans-title>Functional state of endothelium in working age subjects with obstructive sleep apnea syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юшкевич</surname><given-names>Е. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Yushkevich</surname><given-names>E. K.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Картун</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kartun</surname><given-names>L. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Митьковская</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Mitkovskaya</surname><given-names>N. P.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Учреждение здравоохранения «Городская клиническая больница скорой медицинской помощи г. Минска»</institution></aff><aff xml:lang="en"><institution>Minsk City Emergency Hospital</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Белорусский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Belarusian State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>12</day><month>11</month><year>2025</year></pub-date><volume>3</volume><issue>1</issue><fpage>553</fpage><lpage>558</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Юшкевич Е.К., Картун Л.В., Митьковская Н.П., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Юшкевич Е.К., Картун Л.В., Митьковская Н.П.</copyright-holder><copyright-holder xml:lang="en">Yushkevich E.K., Kartun L.V., Mitkovskaya N.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://emcardio.bsmu.by/jour/article/view/256">https://emcardio.bsmu.by/jour/article/view/256</self-uri><abstract><p>В статье рассматриваются лабораторные особенности функционального состояния эндотелия сосудов у лиц трудоспособного возраста с тяжелой и умеренно-тяжелой степенью синдрома обструктивного апноэ сна (СОАС) на основании определения у них уровня биохимических маркеров дисфункции эндотелия.</p></abstract><trans-abstract xml:lang="en"><p>To identify laboratory characteristics of the vascular endothelium function in working age population with moderate to severe obstructive sleep apnea (OSA) syndrome based on the level of endothelial dysfunction biochemical markers.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>синдром обструктивного апноэ сна</kwd><kwd>дисфункция эндотелия</kwd><kwd>сердечно-сосудистый риск</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obstructive sleep apnea syndrome</kwd><kwd>endothelial dysfunction</kwd><kwd>cardiovascular risk</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Anderson T.J., Uehata A., Gerhard M.D., Meredith I.T., Knab S., Delagrange D., Lieberman E.H., Ganz P., Creager M.A., Yeung A.C. 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