<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">emcardio</journal-id><journal-title-group><journal-title xml:lang="ru">Неотложная кардиология и кардиоваскулярные риски</journal-title><trans-title-group xml:lang="en"><trans-title>Emergency Cardiology and Cardiovascular Risks journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2616-633X</issn><publisher><publisher-name>Белорусский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">emcardio-249</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальные научные публикации</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original Scientific Research</subject></subj-group></article-categories><title-group><article-title>Абдоминальное ожирение и постинфарктный кардиосклероз: кардио-метаболический континуум в формировании хронической сердечной недостаточности</article-title><trans-title-group xml:lang="en"><trans-title>Abdominal obesity and postinfarction cardiosclerosis: cardiometabolic continuum in the development of chronic heart failure</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петрова</surname><given-names>Е. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrova</surname><given-names>E. B.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шкребнева</surname><given-names>Э. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Shkrebneva</surname><given-names>E. I</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Статкевич</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Statkevich</surname><given-names>T. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Картун</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kartun</surname><given-names>L. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Митьковская</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Mitkovskaya</surname><given-names>N. P.</given-names></name></name-alternatives><email xlink:type="simple">Mitkovskaya1@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Белорусский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Belarusian State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Государственное учреждение «Минский научно-практический центр хирургии, трансплантологии и гематологии»</institution></aff><aff xml:lang="en"><institution>Minsk Scientific and Practical Center of Surgery, Transplantation and Hematology</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>12</day><month>11</month><year>2025</year></pub-date><volume>3</volume><issue>1</issue><fpage>507</fpage><lpage>512</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Петрова Е.Б., Шкребнева Э.И., Статкевич Т.В., Картун Л.В., Митьковская Н.П., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Петрова Е.Б., Шкребнева Э.И., Статкевич Т.В., Картун Л.В., Митьковская Н.П.</copyright-holder><copyright-holder xml:lang="en">Petrova E.B., Shkrebneva E.I., Statkevich T.V., Kartun L.V., Mitkovskaya N.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://emcardio.bsmu.by/jour/article/view/249">https://emcardio.bsmu.by/jour/article/view/249</self-uri><abstract><p>В статье проанализировано влияние абдоминального ожирения (АО) на постинфарктное ремоделирование миокарда левого желудочка (ЛЖ), реадаптацию к физической нагрузке и течение хронической сердечной недостаточности (ХСН) у лиц трудоспособного возраста с впервые индексированным крупноочаговым инфарктом миокарда (ИМ).</p></abstract><trans-abstract xml:lang="en"><p>The aim of the study was to evaluate the influence of abdominal obesity (АО) on left ventricular myocardium (LV) postinfarction remodeling, readaptation to physical exertion and the course of chronic heart failure in patients of working age with newly diagnosed large-focal myocardial infarction (MI).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая сердечная недостаточность</kwd><kwd>абдоминальное ожирение</kwd><kwd>инфаркт миокарда</kwd><kwd>постинфарктный кардиосклероз</kwd><kwd>лептин</kwd><kwd>мозговой натрийуретический пептид</kwd><kwd>ремоделирование миокарда</kwd><kwd>толерантность к физической нагрузке</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic heart failure</kwd><kwd>abdominal obesity</kwd><kwd>myocardial infarction</kwd><kwd>postinfarction cardiosclerosis</kwd><kwd>leptin</kwd><kwd>brain natriuretic peptide precursor</kwd><kwd>myocardial remodeling</kwd><kwd>exercise capacity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Torabi A., Cleland J.G., Rigby A.S., Sherwi N. Development and course of heart failure after a myocardial infarction in younger and older people. J Geriatr Cardiol, 2014, vol. 11, no. 1, pp. 1–12. doi: 10.3969/j.issn.1671-5411.2014.01.002.</mixed-citation><mixed-citation xml:lang="en">Torabi A., Cleland J.G., Rigby A.S., Sherwi N. Development and course of heart failure after a myocardial infarction in younger and older people. J Geriatr Cardiol, 2014, vol. 11, no. 1, pp. 1–12. doi: 10.3969/j.issn.1671-5411.2014.01.002.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Zotova O.V., Denisevich T.L., Kurlyanskaya E.K., Revtovich O.P. Epidemiologiya hronicheskoy serdechnoy nedostatochnosti v gorode Minske [Epidemiology of chronic hear t failure in Minsk]. Evraz kardiol zhurn., 2016, № 3 [Tezisyi IV Evraziyskogo kongressa kardiologov, Erevan, 10-11 okt. 2016 g.], pp. 182–183. (in Russian).</mixed-citation><mixed-citation xml:lang="en">Zotova O.V., Denisevich T.L., Kurlyanskaya E.K., Revtovich O.P. Epidemiologiya hronicheskoy serdechnoy nedostatochnosti v gorode Minske [Epidemiology of chronic hear t failure in Minsk]. Evraz kardiol zhurn., 2016, № 3 [Tezisyi IV Evraziyskogo kongressa kardiologov, Erevan, 10-11 okt. 2016 g.], pp. 182–183. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Smirnova E.A. Izuchenie rasprostranennosti i etiologii hronicheskoy serdechnoy nedostatochnosti v Ryazanskoy oblasti [Study of prevalence and etiology of chronic heart failure in the Ryazan region]. Ros Kardiolog Zhurnal, 2010, vol. 15, no. 2, pp. 78–83. (in Russian).</mixed-citation><mixed-citation xml:lang="en">Smirnova E.A. Izuchenie rasprostranennosti i etiologii hronicheskoy serdechnoy nedostatochnosti v Ryazanskoy oblasti [Study of prevalence and etiology of chronic heart failure in the Ryazan region]. Ros Kardiolog Zhurnal, 2010, vol. 15, no. 2, pp. 78–83. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Mit’kovskaya N.P. Ostraya serdechnaya nedostatochnost’: e`pidemiologiya, faktory’ riska, prognoz, diagnostika, lechenie i profilaktika [Acute heart failure: epidemiology, risk factors, prognosis, diagnosis, treatment and prevention]. Neotloj Kardiologiya i Kardiovaskulyar Riski, 2018, vol. 2, no. 1, pp. 140–161. (in Russian).</mixed-citation><mixed-citation xml:lang="en">Mit’kovskaya N.P. Ostraya serdechnaya nedostatochnost’: e`pidemiologiya, faktory’ riska, prognoz, diagnostika, lechenie i profilaktika [Acute heart failure: epidemiology, risk factors, prognosis, diagnosis, treatment and prevention]. Neotloj Kardiologiya i Kardiovaskulyar Riski, 2018, vol. 2, no. 1, pp. 140–161. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Lopatin Yu.M. Rekomendatsii ESC po diagnostike i lecheniyu ostroy i hronicheskoy serdechnoy nedostatochnosti 2016 [ESC Guidelines for the diagnosis and treatment of acute and chronic heart filature 2016]. Ros Kardiolog Zhurnal, 2017, no. 1, pp. 7–81. doi.org/10.15829/1560-4071-2017-1-7-81. (in Russian).</mixed-citation><mixed-citation xml:lang="en">Lopatin Yu.M. Rekomendatsii ESC po diagnostike i lecheniyu ostroy i hronicheskoy serdechnoy nedostatochnosti 2016 [ESC Guidelines for the diagnosis and treatment of acute and chronic heart filature 2016]. Ros Kardiolog Zhurnal, 2017, no. 1, pp. 7–81. doi.org/10.15829/1560-4071-2017-1-7-81. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Polonetskiy L.Z., Gelis L.G., Podpalov V.P. Kornelyuk, I.V., Mironchik, V.V. Stelmashok, V.I. Polonetskiy, O.L. Diagnostika i lecheniye ostrykh koronarnykh sindromov s pod”yemom i bezpod”yema segment ST na EKG: nats. rekomendatsii [Diagnosis and treatment of acute coronary syndromes with ascent and without liftin ST segment on ECG: nat. recommendations]. Minsk: Profes. Izd., 2011. 64 p. (in Russian).</mixed-citation><mixed-citation xml:lang="en">Polonetskiy L.Z., Gelis L.G., Podpalov V.P. Kornelyuk, I.V., Mironchik, V.V. Stelmashok, V.I. Polonetskiy, O.L. Diagnostika i lecheniye ostrykh koronarnykh sindromov s pod”yemom i bezpod”yema segment ST na EKG: nats. rekomendatsii [Diagnosis and treatment of acute coronary syndromes with ascent and without liftin ST segment on ECG: nat. recommendations]. Minsk: Profes. Izd., 2011. 64 p. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Petrova E.B., Statkevich T.V., Ponomarenco I.N., Mitkovskaya N.P. Postinfarktnoye remodelirovaniye levogo zheludochka: nekotoryye patogeneticheskiye aspekty [Postinfarction left ventricular remodeling: some pathogenetic aspects]. Voen Medicine, 2015, no. 1, pp. 116–122. (in Russian).</mixed-citation><mixed-citation xml:lang="en">Petrova E.B., Statkevich T.V., Ponomarenco I.N., Mitkovskaya N.P. Postinfarktnoye remodelirovaniye levogo zheludochka: nekotoryye patogeneticheskiye aspekty [Postinfarction left ventricular remodeling: some pathogenetic aspects]. Voen Medicine, 2015, no. 1, pp. 116–122. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Konstam M.A., Kramer D.G., Patel A.R., Maron M.S, Udelson J.E. Left Ventricular Remodeling in Heart Failure. Current Concepts in Clinical Significance and Assessment. JACC Cardiovasc Imaging, 2011, vol. 4, no. 1, pp. 98–108.doi.org/10.1016/j.jcmg.2010.10.008.</mixed-citation><mixed-citation xml:lang="en">Konstam M.A., Kramer D.G., Patel A.R., Maron M.S, Udelson J.E. Left Ventricular Remodeling in Heart Failure. Current Concepts in Clinical Significance and Assessment. JACC Cardiovasc Imaging, 2011, vol. 4, no. 1, pp. 98–108.doi.org/10.1016/j.jcmg.2010.10.008.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Mitkovskaya N.P., Petrova E.B. Abdominalnoe ozhireniev formirovanii hronicheskoy serdechnoy nedostatochnosti posle perenesennogo krupnoochagovogo infarkta miokarda [Abdominal obesity in the formation of chronic heart failure after suffering a major myocardial infarction]. Vestsi NAN belarusi. Ser med navuk, 2017, no. 4, pp. 86-92. (in Russian).</mixed-citation><mixed-citation xml:lang="en">Mitkovskaya N.P., Petrova E.B. Abdominalnoe ozhireniev formirovanii hronicheskoy serdechnoy nedostatochnosti posle perenesennogo krupnoochagovogo infarkta miokarda [Abdominal obesity in the formation of chronic heart failure after suffering a major myocardial infarction]. Vestsi NAN belarusi. Ser med navuk, 2017, no. 4, pp. 86-92. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Cornier M.A., Marshall J.A., Hill J.O., Maahs D.M., Eckel R.H. Prevention of Overweight/Obesity as a Strategy to Optimize Cardiovascular Health. Circulation, 2011, vol. 124, no. 7, pp. 840–850. doi: 10.1161/CIRCULATIONAHA.110.968461.</mixed-citation><mixed-citation xml:lang="en">Cornier M.A., Marshall J.A., Hill J.O., Maahs D.M., Eckel R.H. Prevention of Overweight/Obesity as a Strategy to Optimize Cardiovascular Health. Circulation, 2011, vol. 124, no. 7, pp. 840–850. doi: 10.1161/CIRCULATIONAHA.110.968461.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Kershaw E.E., Flier J.S. Adipose Tissue as an Endocrine Organ. J Clin Endocrinol. Metab, 2004, vol. 89, no. 6, рр. 2548–2556.</mixed-citation><mixed-citation xml:lang="en">Kershaw E.E., Flier J.S. Adipose Tissue as an Endocrine Organ. J Clin Endocrinol. Metab, 2004, vol. 89, no. 6, рр. 2548–2556.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Nikitin N.P., Klinand D.F. Primenenie tkanevoy miokardialnoy doppleroehokardiografii v kardiologii [Application of tissue myocardial Doppler echocardiography in cardiology]. Kardiologiya, 2002, no. 3, pp. 66–79. (in Russian).</mixed-citation><mixed-citation xml:lang="en">Nikitin N.P., Klinand D.F. Primenenie tkanevoy miokardialnoy doppleroehokardiografii v kardiologii [Application of tissue myocardial Doppler echocardiography in cardiology]. Kardiologiya, 2002, no. 3, pp. 66–79. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Bokeriya L.A., Bokeriya O.L., Averina I.I., Berseneva M.A. Ocenka remodelirovaniya levogo zheludochka: Uchebnoe posobie dlya vrachej [Assessment of left ventricular remodeling: A manual for physicians]. Moscow: NCSSH im. A. N. Bakuleva RAMN, 2009, 36 p. (in Russian).</mixed-citation><mixed-citation xml:lang="en">Bokeriya L.A., Bokeriya O.L., Averina I.I., Berseneva M.A. Ocenka remodelirovaniya levogo zheludochka: Uchebnoe posobie dlya vrachej [Assessment of left ventricular remodeling: A manual for physicians]. Moscow: NCSSH im. A. N. Bakuleva RAMN, 2009, 36 p. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Luchner A., Möckel M., Spanuth E., Möcks J., Peetz D., Baum H., Spes C., Wrede C.E., Vollert J., Müller R., Katus H., Giannitsis E. N-terminal pro brain natriuretic peptide in the management of patients in the medical emergency department (PROMPT): correlation with disease severity, utilization of hospital resources, and prognosis in a large, prospective, randomized multicentre trial. Eur J Heart Fail, 2012, vol. 14, no. 3, pp. 259–267.</mixed-citation><mixed-citation xml:lang="en">Luchner A., Möckel M., Spanuth E., Möcks J., Peetz D., Baum H., Spes C., Wrede C.E., Vollert J., Müller R., Katus H., Giannitsis E. N-terminal pro brain natriuretic peptide in the management of patients in the medical emergency department (PROMPT): correlation with disease severity, utilization of hospital resources, and prognosis in a large, prospective, randomized multicentre trial. Eur J Heart Fail, 2012, vol. 14, no. 3, pp. 259–267.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Wirth J., Buijsse B., di Giuseppe R., Fritsche A., Hense H.W., Westphal S., Isermann B., Boeing H., Weikert C. Relationship between N-Terminal Pro-Brain Natriuretic Peptide, Obesity and the Risk of Heart Failure in Middle-Aged German Adults. PLoS One, 2014, vol. 9, no. 11, pp. e113710. doi.org/10.1371/journal.pone.0113710.</mixed-citation><mixed-citation xml:lang="en">Wirth J., Buijsse B., di Giuseppe R., Fritsche A., Hense H.W., Westphal S., Isermann B., Boeing H., Weikert C. Relationship between N-Terminal Pro-Brain Natriuretic Peptide, Obesity and the Risk of Heart Failure in Middle-Aged German Adults. PLoS One, 2014, vol. 9, no. 11, pp. e113710. doi.org/10.1371/journal.pone.0113710.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Sierra-Johnson J., Romero-Corral A., Lopez-Jimenez F., Gami A.S., Sert Kuniyoshi F.H., Wolk R., Somers V.K. Relation of Increased Leptin Concentrations to History of Myocardial Infarction and Stroke in the United States Population. Am J Cardiol, 2007, vol. 100, no. 2, рр. 234–239.</mixed-citation><mixed-citation xml:lang="en">Sierra-Johnson J., Romero-Corral A., Lopez-Jimenez F., Gami A.S., Sert Kuniyoshi F.H., Wolk R., Somers V.K. Relation of Increased Leptin Concentrations to History of Myocardial Infarction and Stroke in the United States Population. Am J Cardiol, 2007, vol. 100, no. 2, рр. 234–239.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Belenkova YU.N., Oganova R.G. eds. Kardiologiya : nac. ruk. [Cardiology: nat. hands’]. Moscow : Ge`otar-Media, 2010, 1232 p. (in Russian).</mixed-citation><mixed-citation xml:lang="en">Belenkova YU.N., Oganova R.G. eds. Kardiologiya : nac. ruk. [Cardiology: nat. hands’]. Moscow : Ge`otar-Media, 2010, 1232 p. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Shammas R.L, Khan N.U.A., Nekkanti R., Movahed A. Diastolic heart failure and left ventricular diastolic dysfunction: What we know, and what we don’t know! Int J Cardiol, 2007, vol. 115, no. 3, pp. 284–292.</mixed-citation><mixed-citation xml:lang="en">Shammas R.L, Khan N.U.A., Nekkanti R., Movahed A. Diastolic heart failure and left ventricular diastolic dysfunction: What we know, and what we don’t know! Int J Cardiol, 2007, vol. 115, no. 3, pp. 284–292.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
