emcardioНеотложная кардиология и кардиоваскулярные рискиEmergency Cardiology and Cardiovascular Risks journal2616-633XБелорусский государственный медицинский университетemcardio-225Research ArticleОригинальные научные публикацииOriginal Scientific ResearchВзаимосвязь полиморфизма гена HIF-1α с риском развития синдрома обструктивного апноэ/гипопноэ сна у пациентов с фибрилляцией предсердий, страдающих ишемической болезнью сердца и/или артериальной гипертензиейAssociation of HIF-1α genetic polymorphism with the risk of obstructive sleep apnea-hypopnea syndrome in atrial fibrillation patients with ischemic heart disease and/or arterial hypertensionБалабановичТ. И.BalabanovichT. I.ШишкоВ. И.ShishkoV. I.СтепуроТ. Л.StepuroT. L.ШуликаВ. Р.ShulikaV. R.УО «Гродненский государственный медицинский университет»Grodno State Medical University20191111202532666–671Copyright © Балабанович Т.И., Шишко В.И., Степуро Т.Л., Шулика В.Р., 20252025Балабанович Т.И., Шишко В.И., Степуро Т.Л., Шулика В.Р.Balabanovich T.I., Shishko V.I., Stepuro T.L., Shulika V.R.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://emcardio.bsmu.by/jour/article/view/225

Цель: изучить ассоциацию полиморфного варианта С1772T гена фактора-1α, индуцируемого гипоксией (от англ. HIF-1α – hypoxia inducible factor-1α) с риском развития синдрома обструктивного апноэ/гипопноэ сна (СОАГС) у пациентов с фибрилляцией предсердий (ФП) на фоне ишемической болезни сердца (ИБС) и/или артериальной гипертензии (АГ).

Aim: to explore the relationship between hypoxia inducible factor-1α (HIF-1α) (С1772T) gene polymorphism and the risk of obstructive sleep apnea-hypopnea syndrome (OSAHS) in atrial fibrillation (AF) patients with ischemic heart disease and/or arterial hypertension.

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The authors declare that there are no conflicts of interest present.