emcardioНеотложная кардиология и кардиоваскулярные рискиEmergency Cardiology and Cardiovascular Risks journal2616-633XБелорусский государственный медицинский университетemcardio-187Research ArticleОригинальные научные публикацииOriginal Scientific ResearchВозбудители вирусных миокардитовThe causative agents of viral myocarditisАмвросьеваТ. В.AmvrosievaT. V.МитьковскаяН. П.MitkovskayaN. P.БогушЗ. Ф.BohushZ. F.АриновичФ. С.ArinovichA. S.БалышЕ. М.BalyshE. M.Государственное учреждение «РНПЦ эпидемиологии и микробиологии»Republican Scientific and Practical Center of Epidemiology and MicrobiologyБелорусский государственный медицинский университетEducational Institution Belarusian State Medical University20203010202541817823Copyright © Амвросьева Т.В., Митьковская Н.П., Богуш З.Ф., Аринович Ф.С., Балыш Е.М., 20252025Амвросьева Т.В., Митьковская Н.П., Богуш З.Ф., Аринович Ф.С., Балыш Е.М.Amvrosieva T.V., Mitkovskaya N.P., Bohush Z.F., Arinovich A.S., Balysh E.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://emcardio.bsmu.by/jour/article/view/187

В статье изложен алгоритм вирусологического обследования пациентов с клинически подозреваемым вирусным миокардитом, и приведены результаты его использования на группе из 49 пациентов в отношении 12 возбудителей вирусных инфекций – цитомегаловируса, вируса Эпштейна-Барр, варицелла-зостер вируса, вируса герпеса человека 6 типа, вирусов герпеса 1 и 2 типов, энтеровирусов, парвовируса В 19, вируса гепатита С, вирусов гриппа А и В, риновирусов и аденовирусов. Наличие серологических маркеров вирусных инфекций (противовирусных IgM) выявлено у 42,1% пациентов, генетический материал возбудителей (РНК/ДНК) в сыворотке крови – у 16,0% пациентов, в тканях сердца – у 75,0% обследованных. Среди выявленных в биологическом материале вирусных патогенов доминировали аденовирусы, парвовирус В 19 и вирус герпеса человека 6 типа. По данным серодиагностики наиболее часто в сыворотках крови обнаруживались IgM к энтеровирусам

The article describes the algorithm of virological examination of patients with clinically suspected viral myocarditis and presents the results of its use in a group of 49 patients with respect to 12 causative agents of viral infections - cytomegalovirus, Epstein-Barr virus, varicella-zoster virus, human herpes virus type 6, herpes viruses types 1 and 2, enteroviruses, parvovirus B 19, hepatitis C virus, influenza A and B viruses, rhinoviruses and adenoviruses. The presence of serological markers of viral infections (antiviral IgM) was detected in 42.1% of patients, the genetic material of pathogens (RNA / DNA) in the blood serum in 16.0% of patients, in heart tissues – in 75.0%. Among the viral pathogens revealed in the biological material, adenoviruses, parvovirus B 19, and human herpes virus type 6 dominated. According to serodiagnosis IgM to enteroviruses was most often detected in blood serum.

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The authors declare that there are no conflicts of interest present.