emcardioНеотложная кардиология и кардиоваскулярные рискиEmergency Cardiology and Cardiovascular Risks journal2616-633XБелорусский государственный медицинский университет10.51922/2616-633X.2021.5.2.1145emcardio-147Research ArticleОригинальные научные публикацииOriginal Scientific ResearchПрименение фотомодификации крови низкоинтенсивным оптическим излучением в комплексном лечении пациентов с нестабильной стенокардиейApplication of photomodification of blood using low-intensity optical radiation in the combination treatment of patients with unstable anginaЛаскинаО. В.LaskinaO.ЗалесскаяГ. А.ZalesskayaG.МитьковскаяН. П.MitkovskayaN.Белорусский государственный медицинский университетBelarusian State Medical UniversityИнститут физики им. Б. И. Степанова НАН БеларусиScientific Institution B.I. Stepanov Institute of Physics of the National Academy of Scienses of Belarus2021221020255111451150Copyright © Ласкина О.В., Залесская Г.А., Митьковская Н.П., 20252025Ласкина О.В., Залесская Г.А., Митьковская Н.П.Laskina O., Zalesskaya G., Mitkovskaya N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://emcardio.bsmu.by/jour/article/view/147

Изучено воздействие in vivo низкоинтенсивного оптического излучения (НИОИ) на кровь пациентов с нестабильной стенокардией (НС). В комплексную терапию пациентов с НС, получавших медикаментозную терапию, а именно дезагреганты (аспирин, клопидогрел), антикоагулянты (низкомолекулярные гепарины), бета-адреноблокаторы, ингибиторы ангиотензинпревращающего фермента, статины, включалось надвенное лазерное облучение крови и ультрафиолетовая модификация крови. Показано, что применение НИОИ в комплексной терапии пациентов с НС приводит к положительным сдвигам в системе утилизации кислорода. На всех стадиях светового воздействия изучены изменения: спектров поглощения образцов крови пациентов, характеристик оксигенации крови и содержания продуктов метаболизма

The in vivo effect of low-intensity optical radiation (LIOR) on the blood of patients with unstable angina (UA) was studied. The integration of LIOR in the combined therapy of patients with UA proved to result in positive changes in the oxygen uptake system. Changes in the absorption spectra of the patients’ blood samples, blood oxygenation characteristics, and the proportion of metabolic products were studied at all stages of light exposure. The absorption of LIOR by the blood was found to lead to its photomodifica tion, which was manifested in changes of the partial pressure of blood gases, the content of oxyhemoglobin and the degree of saturation of hemoglobin with oxygen. LIOR affects the oxygen exchange in the body of patients with UA, changes the delivery and consumption of oxygen by tissues, initiates positive changes in the balance between the production of reactive oxygen intermediates, acting as physiologically active compounds, and their inhibition by antioxidant systems.

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The authors declare that there are no conflicts of interest present.