emcardioНеотложная кардиология и кардиоваскулярные рискиEmergency Cardiology and Cardiovascular Risks journal2616-633XБелорусский государственный медицинский университет10.51922/2616-633X.2021.5.2.1109emcardio-138Research ArticleМастер-классMaster-classНезависимые предикторы и прогнозирование инфаркта миокарда в отдаленном периоде у пациентов с нестабильной стенокардией после стентирования коронарных артерийIndependent predictors and prognosis of long-term myocardial infarction in patients with unstable angina after coronary artery stentingМедведеваЕ. А.MiadzvedzevaA.ГелисЛ. Г.GelisL.ПолонецкийО. Л.PolonetskyO.РусскихИ. И.RusskikhI.ГУ Республиканский научно-практический центр «Кардиология»Republican Scientific and Practical Centre «Cardiology»2021221020255111091120Copyright © Медведева Е.А., Гелис Л.Г., Полонецкий О.Л., Русских И.И., 20252025Медведева Е.А., Гелис Л.Г., Полонецкий О.Л., Русских И.И.Miadzvedzeva A., Gelis L., Polonetsky O., Russkikh I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://emcardio.bsmu.by/jour/article/view/138

Цель: разработать независимые предикторы для прогнозирования инфаркта миокарда в отдаленном периоде у пациентов с нестабильной стенокардией после стентирования коронарных артерий по результатам семилетнего наблюдения. Материалы и методы. За период 2014 г. – 2015 г. в исследование включено 165 пациентов с нестабильной стенокардией и стентированием коронарных артерий. Стентирование выполнялось на 3,2±1,6 сутки от поступления в стационар, использовались стенты с лекарственным покрытием, среднее количество стентов – 2,1±0,78 на человека. Всем пациентам выполнялось определение уровня тропонина I, миелопероксидазы, С-реактивного белка; проводилась оценка коагуляционного гемостаза, выполнение теста генерации тромбина, агрегатограмма. Пациентам выполнялась эхокардиография, коронароангиография. Двойная антитромботическая терапия назначалась на 12 месяцев. Срок наблюдения составил 7,0±1,6 года.

Objective. to develop independent predictors for predicting long-term myocardial infarction (MI) in patients (pts) with unstable angina (UA) after coronary artery stenting (PCI) based on the results of a seven-year follow-up. Materials and Methods. The study involved 165 pts with UA and coronary artery stenting (PCI). PCI was performed in 3.2±1.6 days after admission to the in-patient department. Drug-coated stents (Xience V and Biomatrix) were used, the average number of stents was 2.1±0.8 per person, the average length of the stented area was 43.12±25.6 mm, and the average diameter of the implanted stents was 3.12±0.5 mm. All patients were assessed for troponin I, myeloperoxidase, and C-reactive protein levels; coagulation hemostasis was assessed; and a thrombin generation test was performed. The aggregatogram was performed on the analyzer Multiplate (ASPI-test, ADP-test). The patients underwent echocardiography, coronary angiography. Double antithrombotic therapy with clopidogrel 75 mg and acetylsalicylic acid 75 mg was prescribed for 12 months. The follow-up period was 7.0±1.6 years.

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The authors declare that there are no conflicts of interest present.