emcardioНеотложная кардиология и кардиоваскулярные рискиEmergency Cardiology and Cardiovascular Risks journal2616-633XБелорусский государственный медицинский университет10.51922/2616-633X.2022.6.1.1519emcardio-110Research ArticleОригинальные научные публикацииOriginal Scientific ResearchВлияние выраженности бронхиальной обструкции на выживаемость пациентов с немелкоклеточным раком легкого после хирургического леченияEffect of the airway obstruction severity on the survival of patients with non-small cell lung cancer after surgical treatmentШепетькоМ. Н.ShapetskaM.МириленкоЛ. В.MirilenkoL.ПрохоровА. В.ProkharauA.УО Белорусский государственный медицинский университетBelarusian State Medical UniversityГУ РНПЦ онкологии и медицинской радиологии им. Н.Н. АлександроваState Institution “N. N. Alexandrov National Cancer Center of Belarus”2022270620256115191524Copyright © Шепетько М.Н., Мириленко Л.В., Прохоров А.В., 20252025Шепетько М.Н., Мириленко Л.В., Прохоров А.В.Shapetska M., Mirilenko L., Prokharau A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://emcardio.bsmu.by/jour/article/view/110

Рак легкого представляет медико-социальную проблему. Показатели функции внешнего дыхания (ФВД), которые были получены в результате спирометрии, статистически значимо влияют на общую выживаемость пациентов с немелкоколеточным раком легкого.Цель исследования: установить роль показателей, характеризующих степень бронхиальной обструкции у пациентов с немелкоклеточным раком легкого I-III стадий и оценить её влияние на выживаемость пациентов после хирургического лечения.Материал исследования: в исследование включены 303 пациента с немелкоклеточным раком легкого (НМРЛ) I-III стадий, получивших лечение в УЗ «Минский городской клинический онкологический центр» с 2000 по 2018 гг., у которых были определены показатели ФВД и прослежены отдалённые результаты лечения.Результаты и заключение: после хирургического лечения 5-летняя общая выживаемость (ОВ) пациентов с НМРЛ при отсутствии бронхиальной обструкции составила 42,4%, с бронхиальной обструкцией III-IV степени 5-летняя ОВ – 14,8% (р = 0,006).

Lung cancer is a medical and social problem. Pulmonary function parameters that were obtained from spirometry had a statistically significant influence on the overall survival of patients with non-small cell lung cancer.Aim of study: to establish the role of indicators characterizing the severity of airway obstruction in patients with non-small cell lung cancer stages I-III and to assess its effect on the survival of patients after surgical treatment.Material of study: the study included 303 patients with non-small cell lung cancer (NSCLC) in stages I-III, who had been receiving treatment at the Minsk City Clinical Cancer Center from 2000 to 2018, the patients’ indicators of respiratory failure being determined and long-term results of treatment being monitored.Results and conclusion: after surgical treatment, the 5-year overall survival (OS) rate of patients with NSCLC in the absence of bronchial obstruction was 42.4%, and in case of bronchial obstruction of the IIIrd-IVth degree, the 5-year OS was 14.8% (p = 0.006).

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The authors declare that there are no conflicts of interest present.