У.К. Камилова, З.Д. Расулова, Н.А. Нуритдинов, Д.Р. Тагаева
Республиканский специализированный научно-практический медицинский центр терапии и медицинской реабилитации, г. Ташкент
Выявить прогностические факторы развития дисфункции почек (ДП) и разработать метод оценки и прогнозирования ДП у пациентов с хронической сердечной недостаточностью (ХСН). Методы. Всего были обследованы 101 пациент с I-III функциональным классом (ФК) ХСН (согласно классификации Нью-Йоркской Ассоциации кардиологов). Также пациенты были распределены в зависимости от скорости клубочковой фильтрации, определенной расчетным методом по формуле СKD-EPI (рСКФ) на две группы: пациенты с рСКФ ≥ 90 мл/мин (n = 20), с рСКФ < 90 мл/мин (n = 81). Всем пациентам определяли: креатинин (Кр), рСКФ по формуле СKD-EPI, уровень альбумин/креатинина (Ал/Кр) (мг/ммоль) в утренней моче, удельный вес в утренней порции мочи (SG); изучали почечный кровоток по данным допплерографии на уровне общей левой и правой почечной артерии.
ключевые слова: хроническая сердечная недостаточность, прогноз, дисфункция почек, скорость клубочковой фильтрации

для цитирования: У.К. Камилова, З.Д. Расулова, Н.А. Нуритдинов, Д.Р. Тагаева. Прогнозирование развития дисфункции почек у пациентов с хронической сердечной недостаточностью. Неотложная кардиология и кардиоваскулярные риски, 2020, Т. 4, № 1, С. 839–845

Prediction of the development of renal dysfunction in patients with chronic heart failure
U.K. Kamilova, Z.D. Rasulova, N.A. Nuritdinov, D.R. Tagaeva
Aim. To identify prognostic factors for the development of renal dysfunction (RD) and to develop a method for assessing and predicting RD in patients with chronic heart failure (CHF). Methods. Totally, 101 patients with I-III functional class (FC) CHF were examined (according to the classification of the New York Heart Association). Additionally, the patients were distributed depending on the glomerular filtration rate determined by the calculation method according to the formula CKD-EPI (eGFR) into two groups: patients with eGFR ≥ 90 ml/min (n = 20), with eGFR < 90 ml/min (n = 81). In all patients there were determined: creatinine (Cr), eGFR according to the formula SKD-EPI, albumin/creatinine (Al/Cr) (mg/mmol) in morning urine, specific gravity in the morning urine (SG). We also studied renal blood flow according to Doppler ultrasonography readings at the level of the common left and right renal arteries.
keywords: chronic heart failure, prognosis, renal dysfunction, glomerular filtration rate

for references: U.K. Kamilova, Z.D. Rasulova, N.A. Nuritdinov, D.R. Tagaeva. Prediction of the development of renal dysfunction in patients with chronic heart failure. Neotlozhnaya kardiologiya i kardiovaskulyarnye riski [Emergency cardiology and cardiovascular risks], 2020, vol. 4, no. 1, pp. 839–845

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