Т.И. Балабанович, В.И. Шишко, Т.Л. Степуро, В.Р. Шулика
УО «Гродненский государственный медицинский университет»
Цель: изучить ассоциацию полиморфного варианта С1772T гена фактора-1α, индуцируемого гипоксией (от англ. HIF-1α – hypoxia inducible factor-1α) с риском развития синдрома обструктивного апноэ/гипопноэ сна (СОАГС) у пациентов с фибрилляцией предсердий (ФП) на фоне ишемической болезни сердца (ИБС) и/или артериальной гипертензии (АГ).
ключевые слова: фибрилляция предсердий, синдром обструктивного апноэ/гипопноэ сна, HIF-1α

для цитирования: Т.И. Балабанович, В.И. Шишко, Т.Л. Степуро, В.Р. Шулика. Взаимосвязь полиморфизма гена HIF-1α с риском развития синдрома обструктивного апноэ/гипопноэ сна у пациентов с фибрилляцией предсердий, страдающих ишемической болезнью сердца и/или артериальной гипертензией. Неотложная кардиология и кардиооваскулярные риски, 2019, Т. 3, № 2, С. 666–671

Association of HIF-1α genetic polymorphism with the risk of obstructive sleep apnea-hypopnea syndrome in atrial fibrillation patients with ischemic heart disease and/or arterial hypertension
T.I. Balabanovich, V.I. Shishko, T.L. Stepuro, V.R. Shulika
Aim: to explore the relationship between hypoxia inducible factor-1α (HIF-1α) (С1772T) gene polymorphism and the risk of obstructive sleep apnea-hypopnea syndrome (OSAHS) in atrial fibrillation (AF) patients with ischemic heart disease and/or arterial hypertension.
keywords: atrial fibrillation, obstructive sleep apnea-hypopnea syndrome, HIF-1α

for references: T.I. Balabanovich, V.I. Shishko, T.L. Stepuro, V.R. Shulika. Association of HIF-1α genetic polymorphism with the risk of obstructive sleep apnea-hypopnea syndrome in atrial fibrillation patients with ischemic heart disease and/or arterial hypertension. Neotlozhnaya kardiologiya i kardioovaskulyarnye riski [Emergency cardiology and cardiovascular risks], 2019, vol. 3, no. 2, pp. 666–671

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