Факторы риска развития неблагоприятных сердечно-сосудистых событий у пациентов с сочетанием некомпактной и дилатационной кардиомиопатии

С.М. Комиссарова, Н.М. Ринейская, Т.В. Севрук, А.А. Ефимова

ГУ «Республиканский научно-практический центр «Кардиология», 220036, ул. Розы Люксембург, д. 110Б, Минск, Республика Беларусь

Цель – выявить факторы, ассоциированные с неблагоприятными сердечно-сосудистыми событиями в когорте пациентов с сочетанием некомпактной (НКМП) и дилатационной кардиомиопатии (ДКМП) для идентификации пациентов высокого риска.
Материалы и методы. Обследовано 104 пациентов с сочетанием НКМП и ДКМП в возрасте от 31 до 52 лет (медиана возраста 41 года; мужчин – 81; женщин – 23), которым помимо традиционных клинических методов исследования, выполняли магнитно-резонансную томографию (МРТ) сердца с отсроченным контрастированием гадолинием. Конечные точки исследования включали прогрессирование хронической сердечной недостаточности (ХСН) до III функционального класса (ФК) NYHA, требующее госпитализации, желудочковые тахиаритмии и эмболические события.

ключевые слова: некомпактная кардиомиопатия; дилатационная кардиомиопатия; прогрессирующая сердечная недостаточность; желудочковые тахиаритмии; тромбоэмболические события; факторы риска развития кардиоваскулярных событий.

для цитирования: С.М. Комиссарова, Н.М. Ринейская, Т.В. Севрук, А.А. Ефимова. Факторы риска развития неблагоприятных сердечно-сосудистых событий у пациентов с сочетанием некомпактной и дилатационной кардиомиопатии. Неотложная кардиология икардиоваскулярные риски, 2022, Т. 6, № 2, С. 1615–1624.

Risk factors for the development of adverse cardiovascular events in patients with a combination of non-compaction and dilated cardiomyopathy

S. Komissarova, N. Rineiska, T. Sevruk, A. Efimova

The objective is to identify factors associated with adverse cardiovascular events in a cohort of patients with a combination of non-compaction (NCCM) and dilated cardiomyopathy (DCM) in order to reveal high-risk patients. Materials and methods. 104 patients with a combination of NCCM and DCM aged 31 to 52 years (median age 41 years; 81 men; 23 women) were examined, who, in addition to traditional clinical research methods, underwent cardiac magnetic resonance (CMR) imaging with late gadolinium enhancement. The endpoints of the study included progression of chronic heart failure (CHF) to functional class (FC) III NYHA requiring hospitalization, ventricular tachyarrhythmias and thromboembolic events.

keywords: non-compaction cardiomyopathy; dilated cardiomyopathy; progressive heart failure; ventricular tachyarrhythmias; thromboembolic events; risk factors for the development of cardiovascular events.

for references: V.A. Sujayeva. S. Komissarova, N. Rineiska, T. Sevruk, A. Efimova. Risk factors for the development of adverse cardiovascular events in patients with a combination of non-compaction and dilated cardiomyopathy. Neotlozhnaya kardiologiya i kardiovaskulyarnye riski [Emergency cardiology and cardiovascular risks], 2022, vol. 6, no. 2, pp. 1615–1624.

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