О.В. Ласкина, Г.А. Залесская, Н.В. Мащар
Белорусский государственный медицинский университет, Институт физики им. Б.И. Степанова НАН Беларуси
Цель. Определение фотохимических реакций, происходящих в крови пациентов с острым коронарным синдромом без подъёма сегмента ST (ОКСбпST), с последующим изучением механизмов преобразования ультрафиолетовой модификации крови (УФМК) в биологические реакции.
Методы. Изучено 90 образцов крови пациентов с ОКСбпST, в комплексное лечение которых включалась УФМК с забором крови из локтевой вены и воздействием излучения ртутной лампы (аппарат «Надежда»), курс лечения составил 5 процедур, проводимых ежедневно. Сопоставлялись спектры поглощения крови и эритроцитов, результаты оптической оксиметрии, спектрофотометрии, данные общего анализа крови до УФМК, непосредственно во время отдельных процедур и через 30 минут после окончания курса.
ключевые слова: острый коронарный синдром без подъема сегмента ST, ультрафиолетовая модификация крови, кислородный обмен.
для цитирования: О.В. Ласкина, Г.А. Залесская, Н.В. Мащар. Ультрафиолетовая фотомодификация крови у пациентов с острым коронарным синдромом без подъема сегмента ST (Часть 1). Фотохимические реакции. Неотложная кардиология и кардиоваскулярные риски, 2022, Т. 6, № 2, С. 1637–1643.
Ultraviolet blood photomodification in patients with non-ST elevation acute coronary syndrome (part 1). Photochemical reactions
O.V. Laskina, G.A. Zalesskaya, N.V. Mashchar
Objective. To specify photochemical reactions, occurring in the blood of patients with non-ST elevation acute coronary syndrome (NSTE-ACS), followed by the study of the mechanisms of alterations of ultraviolet blood modification (UVBM) into biological reactions.
Methods. We studied 90 blood samples from patients with NSTE-ACS, receiving complex treatment that included UVBM by mercury lamp radiation with blood taken from the ulnar vein (device “Nadezhda”), the course of treatment consisted of 5 procedures conducted daily. We compared absorption spectra of blood and erythrocytes, results of optical oximetry, spectrophotometry, data of general blood analysis before UVBM, during individual procedures and 20–30 minutes after the end of the course.
keywords: non-ST elevation acute coronary syndrome, ultraviolet blood modification, oxygen exchange.
for references: O.V. Laskina, G.A. Zalesskaya, N.V. Mashchar. Ultraviolet blood photomodification in patients with non-ST elevation acute coronary syndrome (Part 1). Photochemical reactions. Neotlozhnaya kardiologiya i kardiovaskulyarnye riski [Emergency cardiology and cardiovascular risks], 2022, vol. 6, no. 2, pp. 1637–1643.
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